Deterioration of lining is a common phenomenon in tunnel engineering that threatens the safety of operating tunnel. For tunnel lining deterioration in rheological rock mass, an analytical model is established which the rheology effect of surrounding rock and deterioration of lining are considered. The surrounding rock displacement and support pressure of tunnel during its service life are obtained. And then the correctness of analytical model is verified by numerical simulation. Subsequently, the sensitivity analyses of deterioration coefficient of lining, thickness of lining, support time, and rheological properties of surrounding rock are carried out by the proposed analytical model. Finally, the service performance of tunnel is discussed. Research shows that under the rheological effect of surrounding rock, support pressure increases with time, while the mechanical properties of support structure decrease with time. Therefore, the time which support structure reaching its yield strength is shortened. Time history curves of support pressure and bearing capacity of lining are then obtained. Based on this, a model for predicting the service life of operating tunnel is established which the rheology effect of surrounding rock and support performance deterioration are considered. Finally, it is stated that the interaction between support and surrounding rock is the core for the long-term safety of operating tunnel.